Bioxys

Adar's Maleimide-Activated OvA

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Catalog number:1026
Name:Adar's Maleimide-Activated OvA
Size:Bulk
Price:0.00
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Extra details

Category:Activated Carrier Proteins
Shipping conditions:Room Temperature
Storage conditions:Frozen
Maximal storage period:2 years
Statements:Stable at room temp for 1 week
Gene:Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

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