(-)-Blebbistatin for cell activation

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About product

Catalog number:2406-1
Name:(-)-Blebbistatin for cell activation
Size:1 mg
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Extra details

Description:Cell-permeable. The active enantiomer of (±)-Blebbistatin (Cat. No. 2405). A selective inhibitor of non-muscle myosin II ATPases. It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC₅₀ = 0.5-5.0 μM), while weakly inhibiting smooth muscle myosin (IC₅₀ = 80 μM). Through these effects, (-)-blebbistatin reversibly blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells.
Peptide sequence:N/A
CAS number:856925-71-8
Molecular weight:292.34
Other name:1,​2,​3,​3a-​tetrahydro-​3aS-​hydroxy-​6-​methyl-​1-​phenyl-​4H-​Pyrrolo[2,​3-​b]quinolin-​4-​one; (S)-Blebbistatin
Molecular formula:C₁₈H₁₆N₂O₂
Physical appearance:Yellow solid
Supplied with:N/A
Is this a salt?:No
Is it cell-permeable?:Yes
Purification:≥98% by HPLC
Reconstitute instructions:DMSO (~25 mg/ml)
Storage condition:-20 ̊C
Shipping condition:gel pack
Maximum time for storage:36 months
Storage instructions:Protect from light and air
Additional description:For cells, cell lines and tissues in culture till half confluency.

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