MMP 17 (MT4-MMP) catalytic domain, His-tagged (Recombinant Protein)

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Catalog number:30 100 402
Name:MMP 17 (MT4-MMP) catalytic domain, His-tagged (Recombinant Protein)
Size:10 µg/ 50µl
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Extra details

Protein type:Recombinant
Protein subtype:EC 3.4.24.-
Protein family:Matrix Metalloproteinases, matrixins
Protein description:MMP17 is a endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Research area interests:Among MMP17 related pathways are Matrix Metalloproteinases and Degradation of the extracellular matrix.
Package form:liquid
Tested applications:Degradation of extracellular Matrix; Screening and evaluation of MMP inhibitors; Antigen standard
Other names:Membrane-Type 4 Matrix Metalloproteinase
Peptide sequence:Q A P A P T K W N K R N L S W R V R T F P R D S P L G H D T V R A L M Y Y A L R V W S D I A P L N F H E V A G S T A D I Q I D L S K A D H N D G Y P F D G P G G T V A H A F F P G H H H T A G D T H F D D D E A W T F R S S D A H G M D L F A V A V H E F G H A I G L S H V A A A H S I M R P Y Y Q G P V G D P L R Y G L P Y E D K V R V W Q L Y G V R E S V S P T A Q P E E P P L E H H H H H H
Available target modification:No
Expression system:E.coli
Product Subtype:protein fragment
Active form?:Yes
Contents:50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl2, 0.1% Triton X-100.
Protein purity:0.8
Molecular weight:24 kDa
UniProt number:Q9ULZ9
Gene number:4326
Abbreviation:MMP17 (partial)
Full name:matrix metallopeptidase 17 (partial)
Other desciption:The catalytic domain of human MT4-MMP is produced by tryptic activation of a recombinant soluble proform purified from E. coli periplasm.
Purification:Mentioned in the data sheet
PubMed citations:See the data sheet
Warnings:For Research Use only.
Shipping conditions:dry ice
Storage condition:Store at -70°C
Technical datasheet:Contact us to receive the datasheet
Source:Recombinants or rec. proteins

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