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Anti-HPV16 E6 protein (2E3) Monoclonal, ALEXA Fluor 594

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About product

Catalog number:GENTObsm-0990M-A594
Name:Anti-HPV16 E6 protein (2E3) Monoclonal, ALEXA Fluor 594
Size:116 microliters
Price:489.00
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Extra details

Type:Conjugated Primary Antibody
Conjugated with:ALEXA FLUOR 594
Host organism:Mouse (Mus musculus)
Target Protein/Peptide:HPV16 E6 protein
Specificity:Highly specific antibody against HPV16 E6 protein
Modification:Not modified
Clonality:Monoclonal Antibodies
Clone:2E3
Concentration:1ug per 1ul
Antigen Source:KLH conjugated synthetic peptide derived from HPV16 E6 protein
Gene ID:1399
Applications:IF(IHC-P)
Applications with corresponding dilutions:IF(IHC-P)(1:50-200)
Cross Reactive species:Virus
Cross Reactive Species details:HPV16
Background information:Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.
Purification method:Purified by Protein G.
Storage:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission:590nm/617nm
Synonyms:E6; HPV16 E6 protein; Human Papilloma Virus; Human papillomavirus type 16 E6; Human papillomavirus type 16; Protein E6; E6 protein; HPV16 E6; HPV16-E6; VE6_HPV16.
Alternative name 1:HPV16 E6 protein (2E3) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
Alternative name 2:HPV16 E6 protein (2E3) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
Advisory:Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
Properties:For facs or microscopy Alexa 1 conjugate.
Conjugation:Alexa Fluor,ALEXA FLUOR® 594
Conjugated:Alexa conjugate 1
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
About:Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

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