Bioxys

Anti-CRP (C11F2) Monoclonal, ALEXA Fluor 594

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About product

Catalog number:GENTObsm-0391M-A594
Name:Anti-CRP (C11F2) Monoclonal, ALEXA Fluor 594
Size:106 microliters
Price:489.00
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Extra details

Type:Conjugated Primary Antibody
Conjugated with:ALEXA FLUOR 594
Host organism:Mouse (Mus musculus)
Target Protein/Peptide:CRPC
Specificity:Highly specific antibody against CRPC
Modification:Not modified
Clonality:Monoclonal Antibodies
Clone:C11F2
Concentration:1ug per 1ul
Antigen Source:Recombinant CRP protein
Gene ID:1401
Applications:IF(IHC-P)
Applications with corresponding dilutions:IF(IHC-P)(1:50-200)
Cross Reactive species:Human (Homo sapiens)
Cross Reactive Species details:No significant cross reactivity is observed
Background information:C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.
Purification method:Purified by Protein G.
Storage:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission:590nm/617nm
Synonyms:C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C Reactive Protein.
Alternative name 1:CRP (C11F2) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
Alternative name 2:CRP (C11F2) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
Advisory:Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
Properties:For facs or microscopy Alexa 1 conjugate.
Conjugation:Alexa Fluor,ALEXA FLUOR® 594
Conjugated:Alexa conjugate 1
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Gene:C reactive proteins are detected by anti-CRP antibodies supplied by GENTAUR.
About:Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

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