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Anti-P53(wt-p53) (D2F7) Monoclonal, ALEXA Fluor 594

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Catalog number:GENTObsm-2346M-A594
Name:Anti-P53(wt-p53) (D2F7) Monoclonal, ALEXA Fluor 594
Size:143 microliters
Price:489.00
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Extra details

Type:Conjugated Primary Antibody
Conjugated with:ALEXA FLUOR 594
Host organism:Mouse (Mus musculus)
Target Protein/Peptide:P53wt-p53
Specificity:Highly specific antibody against P53wt-p53
Modification:Not modified
Clonality:Monoclonal Antibodies
Clone:D2F7
Concentration:1ug per 1ul
Antigen Source:KLH conjugated synthetic peptide derived from human P53(wt-p53)
Gene ID:7157
Applications:IF(IHC-P)
Applications with corresponding dilutions:IF(IHC-P)(1:50-200)
Cross Reactive species:Human (Homo sapiens), Rat (Rattus norvegicus)
Cross Reactive Species details:No significant cross reactivity is observed
Background information:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
Purification method:Purified by Protein G.
Storage:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission:590nm/617nm
Synonyms:Widespread p53; Wtp53; Antigen NY-CO-13; Cellular tumor antigen p53; Cys 51 Stop; HGNC11998; LFS1; p53; p53 Cellular Tumor Antigen; p53 Tumor Suppressor; Phosphoprotein p53; TP53; Transformation related protein 53; TRP53; Tumor protein p53; Tumour Protein p53; P53_HUMAN; TP53.
Alternative name 1:P53(wt-p53) (D2F7) Monoclonal Antibody, ALEXA FLUOR® 594 Conjugated
Alternative name 2:P53(wt-p53) (D2F7) Monoclonal anti-, ALEXA FLUOR 594 Conjugated
Advisory:Cycles of freezing and thawing should be avoided as such cycles may denature the peptide chains of the antibody and reduce its affinity, specificity and reactivity. For antibodies in a liquid form or reconstituted lyophilized antibodies - small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
Properties:For facs or microscopy Alexa 1 conjugate.
Conjugation:Alexa Fluor,ALEXA FLUOR® 594
Conjugated:Alexa conjugate 1
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
About:Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

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