Netrin G2 Antibody

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Catalog number:bs-11103R
Name:Netrin G2 Antibody
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Extra details

Long name:Netrin G2 Primary Polyclonal Antibody
Also known as:Netrin G2 PAb
Category:Primary Antibodies
Target Antigen:Netrin G2
Specificity:This is a highly specific antibody against Netrin G2.
Modification site(s):Unmodified antibody
Clonality:Polyclonal antibody
Clone number:Polyclonal antibody
Concentration:1ug per 1ul
Source:This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Netrin G2
Tested Applications:WB, IHC-P, IF(IHC-P)
Recommended dilutions:WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity:Human, Mouse, Rat
Cross reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen:Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin-1, which is the mammalian homolog of UNC-6 from C. elegans, is largely expressed in the developing nervous system and in mesodermal tissues. Netrin-1 is expressed by the floor plate as either a cell associated protein or in a diffusible form, and it binds to several surface receptor components, including deleted in colorectal cancer (DCC) and neogenin. During embryonic development, netrin-1 diffuses through the neuronal epithelium, where it forms a chemoattractant gradient that directs axonal migration to the ventral midline of the spinal cord. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins, as the cells are repelled, rather than attracted, by the netrin gradient.
Purification method:This antibody was purified via Protein A.
Storage conditions:Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names:Laminet 2; Laminet-2; Laminet2;Lmnt2; Lmnt 2; Lmnt-2; Netrin-G2; NetrinG2; NTNG1; NTNG 1; NTNG-1; NTNG2; NTNG 2; NTNG-2; NTNG2_HUMAN; bA479K20.1; LHLL9381.
Properties:If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation:anticorps

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