Bcr (Tyr360) Antibody

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About product

Catalog number:bs-6258R
Name:Bcr (Tyr360) Antibody
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Extra details

Long name:Bcr (Tyr360) Primary Polyclonal Antibody
Also known as:Bcr (Tyr360) PAb
Category:Primary Antibodies
Target Antigen:Bcr Tyr360
Specificity:This is a highly specific antibody against Bcr Tyr360.
Modification site(s):Tyr360
Clonality:Polyclonal antibody
Clone number:Polyclonal antibody
Concentration:1ug per 1ul
Source:KLH conjugated synthetic phosphopeptide derived from human Bcr around the phosphorylation site of Tyr360 [TT(p-Y)RM]
Gene ID number:613
Tested Applications:WB, IHC-P, IF(IHC-P)
Recommended dilutions:WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity:Human, Mouse, Rat
Cross reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen:A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Purification method:This antibody was purified via Protein A.
Storage conditions:Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names:Bcr phospho Y360; Bcrphospho Y360; P-Bcrphospho Y360; ALL; BCR 1; BCR/ABL FUSION GENE INCLUDED; BCR/FGFR1 FUSION GENE INCLUDED; BCR/PDGFRA FUSION GENE INCLUDED; BCR1; breakpoint cluster region; CML; PHL; BCR_HUMAN.
Properties:If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation:anticorps

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