CRBN Antibody

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Catalog number:bs-11716R
Name:CRBN Antibody
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Extra details

Long name:CRBN Primary Polyclonal Antibody
Also known as:CRBN PAb
Category:Primary Antibodies
Target Antigen:CRBN
Specificity:This is a highly specific antibody against CRBN.
Modification site(s):Unmodified antibody
Clonality:Polyclonal antibody
Clone number:Polyclonal antibody
Concentration:1ug per 1ul
Source:This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRBN
Tested Applications:WB, FCM, IHC-P, IF(IHC-P)
Recommended dilutions:WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Cross reactivity:Human, Mouse, Rat
Cross reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the target antigen:CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.
Purification method:This antibody was purified via Protein A.
Storage conditions:Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Synonym names:Cereblon; DKFZp781K0715; MGC27358; MRT2A; OTTHUMP00000209555; piL; Protein cereblon; Protein x 0001; 2610203G15Rik; 2900045O07Rik; AF229032; AW108261; CRBN_HUMAN.
Properties:If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation:anticorps

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