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Anti- ID2 (Polyclonal), ALEXA Fluor 594

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About product

Catalog number:GENTObs-3515R-A594
Name:Anti- ID2 (Polyclonal), ALEXA Fluor 594
Size:100 microliters
Price:489.00
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Extra details

Type:Conjugated Primary Antibody
Conjugated with:ALEXA FLUOR® 594
Host organism:Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:ID2
Specificity:Due to the similarity of this protein with ID1, this antibody has a chance to have light cross-reactivity with ID1 due to a 77% sequence similarity in the range of our immunogen. ID2
Modification:No modification has been applied to this antibody
Modification site:None
Clonality:Polyclonal Antibody
Clone:Polyclonal Antibodies
Concentration:1ug per 1ul
Subcellular locations:Cytoplasm, Nucleus
Antigen Source:KLH conjugated synthetic peptide derived from human GIG8/ID2
Gene ID:3398
Swiss Prot:Q02363
Applications:IF(IHC-P)
Applications with corresponding dilutions:IF(IHC-P)(1:50-200)
Cross reactive species:Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details:No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information:Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.
Purification method:Purified by Protein A.
Storage:Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission:590nm/617nm
Synonyms:GIG8; ID2A; ID2H; bHLHb26; DNA-binding protein inhibitor ID-2; Class B basic helix-loop-helix protein 26; Inhibitor of DNA binding 2; Inhibitor of differentiation 2; ID2
Also known as:ID2 Polyclonal Antibody
Other name:Anti- ID2 Polyclonal
Advisory:Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties:For facs or microscopy Alexa 1 conjugate.
Conjugation:Alexa Fluor,ALEXA FLUOR® 594
Conjugated:Alexa conjugate 1
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody for research use.
Group:Polyclonals and antibodies
About:Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

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