Mouse Monoclonal IgG1 Anti-3-DG-Imidazolone (Advanced Glycation End Product) [JNH-27]

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Catalog number:IMI043
Name:Mouse Monoclonal IgG1 Anti-3-DG-Imidazolone (Advanced Glycation End Product) [JNH-27]
Size:50 µg
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Extra details

Availability:Please contact us to check the availability
Immunogen:3-DG-derived Imidazolone-HSA
Species reactivity:not relevant
Product presentation:Protein G affinity purified antibody from ascites in stabilized buffer, containing 50% Block Ace (Casein-containing solution, Dainippon Co.) and 0.1% ProClin (Rohm & Haas) as a preservative
Product category:Primary Antibody
Antibody's raised in:Mouse
Antibody's isotype:IgG1
Antibody's clone:JNH-27
Product is supplied as:liquid concentrate
Recommended concentration for use:app. 7 µg/ml (IHC)
Protein concentration:0.25 mg/ml
Tested applications:IHC(C, P)
Recommended secondary reagent:We recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art. No. AE005). If higher sensitivity is required VECTASTAIN Elite ABC Mouse IgG (Art. No. PK-6102) or ABC AP Mouse IgG (Art. No. AK-5002) systems are applicable.
Storage method:Store at -20°C
UniProt number:Go to UniProt/SwissProt
Litterature:1. Shibata N, Nagai R, Miyata S, Jono T, Horiuchi S, Hirano A, Kato S, Sasaki S, Asayama K, Kobayashi M. Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation. Acta Neuropathol (Berl). 2000 Sep; 100(3): 275-284. 2. Niwa T, Katsuzaki T, Miyazaki S, Momoi T, Akiba T, Miyazaki T, Nokura K, Hayase F, Tatemichi N, Takei Y. Amyloid beta 2-microglobulin is modified with imidazolone, a novel advanced glycation end product, in dialysis-related amyloidosis.Kidney Int. 1997 Jan;51(1):187-194. 3. Franke S, Niwa T, Deuther-Conrad W, Sommer M, Hein G, Stein G. Immunochemical detection of imidazolone in uremia and rheumatoid arthritis. Clin Chim Acta. 2000 Oct;300(1-2):29-41. 4. Nakamura S, Miyazaki S, Sakai S, Morita T, Hirasawa Y, Niwa T. Localization of imidazolone in the peritoneum of capd patients: a factor for a loss of ultrafiltration. Am J Kidney Dis. 2001 Oct;38(4 Suppl 1):S107-110. 5. Franke S, Dawczynski J, Strobel J, Niwa T, Stahl P, Stein G. Increased levels of advanced glycation end products in human cataractous lenses. J Cataract Refract Surg. 2003 May;29(5):998-1004.
Tips:*Gentaur antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
About:Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test:Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name:Mus musculus

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