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PKM2 (Tyr105) Antibody, ALEXA FLUOR 594

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About product

Catalog number:bs-3334R-A594
Name:PKM2 (Tyr105) Antibody, ALEXA FLUOR 594
Size:100ul
Price:350.15
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Extra details

Long name:PKM2 (Tyr105) Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
Also known as:Anti-PKM2 Tyr105 PAb ALEXA FLUOR 594
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 594
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:PKM2 Tyr105
Specificity:This is a highly specific antibody against PKM2 Tyr105.
Modification:Phosphorylation
Modification Site:Tyr105
Clonality:Polyclonal
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Immunogen range:97-121/531
Subcellular location:Cytoplasm, Nucleus
Source:KLH conjugated synthetic phosphopeptide derived from human PKM2 around the phosphorylation site of Tyr105
Gene ID Number:5315
Swiss Prot:P14618
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human, Mouse, Rat
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:590nm/617nm
Synonyms:Pyruvate kinase PKM; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; THBP1; Tumor M2-PK; p58; PKM; OIP3; PK2; PK3; PKM2
Properties:For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor,ALEXA FLUOR® 594
Conjugated:Alexa conjugate 1
French translation:anticorps

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