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Androgen Receptor (Ser94) Antibody, ALEXA FLUOR 488

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About product

Catalog number:bs-12473R-A488
Name:Androgen Receptor (Ser94) Antibody, ALEXA FLUOR 488
Size:100ul
Price:350.15
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Extra details

Long name:Androgen Receptor (Ser94) Antibody, ALEXA FLUOR 488 Conjugated
Also known as:Anti-Androgen Receptor Ser94 PAb ALEXA FLUOR 488
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 488
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:Androgen Receptor Ser94
Specificity:This is a highly specific antibody against Androgen Receptor Ser94.
Modification:Phosphorylation
Modification Site:Ser94
Clonality:Polyclonal
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Source:KLH conjugated synthetic phosphopeptide derived from human Androgen Receptor around the phosphorylation site of Ser94
Gene ID Number:367
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:499nm/519nm
Synonyms:Androgen Receptor phospho S94; Androgen Receptor Ser94; Androgen Receptor phospho Ser94; p-Androgen Receptor Ser94; ANDR_HUMAN; HYSP1; AIS; Androgen receptor dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease; AR; DHTR; Dihydro Testosterone Receptor; Dihydrotestosterone receptor; HUMARA; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; Spinal and bulbar muscular atrophy; TFM.
Properties:For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Androgen Receptor (Ser94) Antibody, has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor
Description:The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
French translation:anticorps

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