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Adenomatous Polyposis Coli Antibody, ALEXA FLUOR 594

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Catalog number:bs-3680R-A594
Name:Adenomatous Polyposis Coli Antibody, ALEXA FLUOR 594
Size:100ul
Price:332.75
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Extra details

Long name:Adenomatous Polyposis Coli Antibody, ALEXA FLUOR 594 Conjugated
Also known as:Anti-APC/Adenomatous Polyposis Coli PAb ALEXA FLUOR 594
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 594
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:APC/Adenomatous Polyposis Coli
Specificity:This is a highly specific antibody against APC/Adenomatous Polyposis Coli.
Modification:Unmodified
Modification Site:None
Clonality:Polyclonal
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Immunogen range:2790-2843/2843
Subcellular location:Cytoplasm
Source:This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APC
Gene ID Number:324
Swiss Prot:P25054
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human, Mouse, Rat
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:590nm/617nm
Synonyms:GS; DP2; DP3; BTPS2; DP2.5; PPP1R46; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5; APC
Properties:For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor,ALEXA FLUOR® 594
Conjugated:Alexa conjugate 1
French translation:anticorps

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