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Caspase-9 (Ser196) Antibody, ALEXA FLUOR 488

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Catalog number:bs-5241R-A488
Name:Caspase-9 (Ser196) Antibody, ALEXA FLUOR 488
Size:100ul
Price:350.15
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Extra details

Long name:Caspase-9 (Ser196) Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
Also known as:Anti-Caspase-9 Ser196 PAb ALEXA FLUOR 488
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 488
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:Caspase-9 Ser196
Specificity:This is a highly specific antibody against Caspase-9 Ser196.
Modification:Phosphorylation
Modification Site:Ser196
Clonality:Polyclonal
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Immunogen range:180-220/416
Subcellular location:Nucleus, Mitochondrion
Source:KLH conjugated synthetic phosphopeptide derived from human CASP9 around the phosphorylation site of Ser196
Gene ID Number:842
Swiss Prot:P55211
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:499nm/519nm
Synonyms:MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9
Properties:For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Caspase-9 (Ser196) Antibody, has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor
Description:Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
French translation:anticorps

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