OST-beta Antibody, ALEXA FLUOR 350

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Catalog number:bs-2128R-A350
Name:OST-beta Antibody, ALEXA FLUOR 350
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Long name:OST-beta Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
Also known as:Anti-OST-beta PAb ALEXA FLUOR 350
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 350
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:OST-beta
Specificity:This is a highly specific antibody against OST-beta.
Modification Site:None
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Subcellular location:Extracellular
Source:This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OST-beta
Gene ID Number:123264
Tested applications:FCM, IF(IHC-P)
Recommended dilutions:FCM(1:20-100), IF(IHC-P)(1:50-200)
Crossreactivity:Human, Mouse, Rat
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:343nm/442nm
Synonyms:organic solute transporter beta Ostbeta; Organic solute transporter subunit beta; Ostbeta; Ost beta; OST-beta; OSTB; OSTB_HUMAN.
Properties:For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor,ALEXA FLUOR 350
French translation:anticorps

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