5-Lipoxygenase(Ser271) Antibody, ALEXA FLUOR 594

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Catalog number:bs-3251R-A594
Name:5-Lipoxygenase(Ser271) Antibody, ALEXA FLUOR 594
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Long name:5-Lipoxygenase(Ser271) Antibody, ALEXA FLUOR 594 Conjugated
Also known as:Anti-5-Lipoxygenase Ser271 PAb ALEXA FLUOR 594
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 594
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:5-Lipoxygenase Ser271
Specificity:This is a highly specific antibody against 5-Lipoxygenase Ser271.
Modification Site:Ser271
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Source:KLH conjugated synthetic phosphopeptide derived from rat 5-Lipoxygenase around the phosphorylation site of Ser271
Gene ID Number:240
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human, Mouse, Rat
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:590nm/617nm
Synonyms:5-lipoxygenase; 5 LO; 5LPG; ALOX 5; ALOX5; Arachidonate 5 lipoxygenase; Arachidonic acid 5 lipoxygenase; Leukotriene A4 synthase; LOG 5; LOG5; MGC163204; LOX5_HUMAN.
Properties:For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor,ALEXA FLUOR® 594
Conjugated:Alexa conjugate 1
French translation:anticorps

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