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IRS-2 Antibody, ALEXA FLUOR 488

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About product

Catalog number:bs-0173R-A488
Name:IRS-2 Antibody, ALEXA FLUOR 488
Size:100ul
Price:332.75
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Extra details

Long name:IRS-2 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
Also known as:Anti-IRS-2 PAb ALEXA FLUOR 488
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 488
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:IRS-2
Specificity:This is a highly specific antibody against IRS-2.
Modification:Unmodified
Modification Site:None
Clonality:Polyclonal
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Immunogen range:540-590/1338
Subcellular location:Cytoplasm
Source:This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IRS-2
Gene ID Number:8660
Swiss Prot:Q9Y4H2
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human, Rat
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:499nm/519nm
Synonyms:IRS-2; Insulin receptor substrate 2; IRS2
Properties:For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the IRS-2 Antibody, has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor
French translation:anticorps

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