AMPK gamma 1/2/3 Antibody, ALEXA FLUOR 488

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Catalog number:bs-9446R-A488
Name:AMPK gamma 1/2/3 Antibody, ALEXA FLUOR 488
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Long name:AMPK gamma 1/2/3 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
Also known as:Anti-AMPK gamma 1/2/3 PAb ALEXA FLUOR 488
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 488
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:AMPK gamma 1/2/3
Specificity:This is a highly specific antibody against AMPK gamma 1/2/3.
Modification Site:None
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Immunogen range:280-330/569
Subcellular location:Extracellular, Cytoplasm, Nucleus
Source:This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PRKAG2/AMPKγ2
Gene ID Number:5571, 51422, 53632,
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human, Mouse, Rat
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:AMPK is a heterotrimeric complex comprising a catalytic a subunit and regulatory b and g subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase and inhibition of dephosphorylation. Activated AMPK can phosphorylate and regulate in vivo hydroxy-methylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively. The human AMPKa1 and AMPKa2 genes encode 548 amino acid and 552 amino acid proteins, respectively. Human AMPKb1 encodes a 271 amino acid protein and human AMPKb2 encodes a 272 amino acid protein. The human AMPKg1 gene encodes a 331 amino acid protein. Human AMPKg2 and AMPKg3, which are 569 and 492 amino acid proteins, respectively, contain unique N-terminal domains and may participate directly in the binding of AMP within the AMPK complex.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:499nm/519nm
Synonyms:5'-AMP-activated protein kinase subunit gamma-2; AAKG; AMPK gamma2; AMPK gamma 2; AMPK subunit gamma 2; CMH6; H91620p; AMPKg; AMPK subunit gamma-1; AMPK gamma1; AMPKg3; AMPK subunit gamma-3; AMPK gamma3.
Properties:For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the AMPK gamma 1/2/3 Antibody, has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor
French translation:anticorps

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