Bioxys

HDAC6 Antibody, ALEXA FLUOR 594

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Catalog number:bs-2811R-A594
Name:HDAC6 Antibody, ALEXA FLUOR 594
Size:100ul
Price:332.75
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Extra details

Long name:HDAC6 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
Also known as:Anti-HDAC6 PAb ALEXA FLUOR 594
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 594
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:HDAC6
Specificity:This is a highly specific antibody against HDAC6.
Modification:Unmodified
Modification Site:None
Clonality:Polyclonal
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Immunogen range:330-380/1215
Subcellular location:Cytoplasm, Nucleus
Source:This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HDAC6
Gene ID Number:10013
Swiss Prot:Q9UBN7
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human, Mouse, Rat
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. In addition to its protein deacetylase activity, plays a key role in the degradation of misfolded proteins: when misfolded proteins are too abundant to be degraded by the chaperone refolding system and the ubiquitin-proteasome, mediates the transport of misfolded proteins to a cytoplasmic juxtanuclear structure called aggresome. Probably acts as an adapter that recognizes polyubiquitinated misfolded proteins and target them to the aggresome, facilitating their clearance by autophagy.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:590nm/617nm
Synonyms:HD6; JM21; CPBHM; PPP1R90; Histone deacetylase 6; HDAC6; KIAA0901
Properties:For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor,ALEXA FLUOR® 594
Conjugated:Alexa conjugate 1
French translation:anticorps

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