CLSTN1/Calsyntenin 1 Antibody, ALEXA FLUOR 350

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Catalog number:bs-11644R-A350
Name:CLSTN1/Calsyntenin 1 Antibody, ALEXA FLUOR 350
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Extra details

Long name:CLSTN1/Calsyntenin 1 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
Also known as:Anti-CLSTN1/Calsyntenin 1 PAb ALEXA FLUOR 350
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 350
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:CLSTN1/Calsyntenin 1
Specificity:This is a highly specific antibody against CLSTN1/Calsyntenin 1.
Modification Site:None
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Subcellular location:Extracellular
Source:This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Calsyntenin 1
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human, Mouse, Rat
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:Members of the calsyntenin protein family are localized to the post-synaptic membrane of exicitatory central nervous system (CNS) synapses. Calsyntenin-1, also known as CSTN1, PIK3CD, Alzheimer-related cadherin-like protein, non-classical cadherin XB31alpha, KIAA0911, ALC-ALPHA, alcalpha1, alcalpha2 or FLJ32258, is a 981 amino acid single-pass type I membrane protein that localizes to the membrane of endoplasmic reticulum, Golgi apparatus, cell projections and postsynaptic cells. Expressed in brain, calsyntenin-1 is also found at lower levels in placenta, skeletal muscle, heart and kidney. Calsyntenin-1 binds synaptic Ca2+ with its cytoplasmic domain and plays a role in extracellular proteolysis. Calsyntenin-1 is also known to form a complex with X11 Beta and APP to suppress the metabolic cleavage of APP, and docks vesicular cargo to KLC1. Calsyntenin-1 may be related to the development or progression of Alzheimer’s disease, and two calsyntenin-1 isoforms are produced as a result of alternative splicing events.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:343nm/442nm
Synonyms:Alc alpha; Alc-alpha; Alcadein alpha 1; Alcadein alpha; Alcadein-alpha; alcalpha1; alcalpha2; Alzheimer related cadherin like protein; Alzheimer-related cadherin-like protein; Calsyntenin-1; Calsyntenin1; CLSTN 1; Clstn1; CS1; CSTN1; CSTN1_HUMAN; CTF1-alpha; FLJ32258; KIAA0911; Non classical cadherin XB31alpha; Non-classical cadherin XB31alpha; PIK3CD; SAlc-alpha; XB31alpha.
Properties:For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor,ALEXA FLUOR 350
French translation:anticorps

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