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15 Lipoxygenase 1 Antibody, ALEXA FLUOR 647

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Catalog number:bs-6505R-A647
Name:15 Lipoxygenase 1 Antibody, ALEXA FLUOR 647
Size:100ul
Price:332.75
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Extra details

Long name:15 Lipoxygenase 1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
Also known as:Anti-15 Lipoxygenase 1 PAb ALEXA FLUOR 647
Category:Conjugated Primary Antibodies
Conjugated with:ALEXA FLUOR® 647
Host Organism:Rabbit (Oryctolagus cuniculus)
Target Antigen:15 Lipoxygenase 1
Specificity:This is a highly specific antibody against 15 Lipoxygenase 1.
Modification:Unmodified
Modification Site:None
Clonality:Polyclonal
Clone:Polyclonal antibody
Concentration:1ug per 1ul
Immunogen range:610-662/662
Subcellular location:Cytoplasm
Source:This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ALOX15/15 Lipoxygenase 1
Gene ID Number:246
Swiss Prot:P16050
Tested applications:IF(IHC-P)
Recommended dilutions:IF(IHC-P)(1:50-200)
Crossreactivity:Human, Mouse, Rat
Cross-reactive species details:Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen:Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.
Purification:Purified by Protein A.
Storage conditions:Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Excitation emission:650nm/665nm
Synonyms:12-LOX; 15LOX-1; 15-LOX-1; Arachidonate 15-lipoxygenase; 15-LOX; 12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate omega-6 lipoxygenase; ALOX15; LOG15
Properties:For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the 15 Lipoxygenase 1 Antibody, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation:Alexa Fluor,ALEXA FLUOR 647
French translation:anticorps

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