Bioxys

anti-Phospho-JNK/SAPK Antibody

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About product

Catalog number:3589-100
Name:anti-Phospho-JNK/SAPK Antibody
Size:Phospho-JNK/SAPK Antibody
Price:403.00
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Extra details

Target of this antibody::Phospho-JNK/SAPK
Alternative names of antibody target::c-Jun kinase, JNK , JNK 1 , JAK1A , MAPK8 , MAPK 8 , SAPK 1 , SAPK1 , Kinase JNK1 , Stress activated protein kinase
Background information::The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-α and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71.
Antibody host::Rabbit
Clonality of antibody::Polyclonal
Isotype::Rabbit IgG
This antibody reacts with::Human, mouse, rat
Immunogene sequence::Synthetic phospho-peptide corresponding to residues surrounding Thr183/Tyr185 of human SAPK/JNK
Concentration of antibody::0.5 mg/ml
Form of antibody::Liquid
Formulation of this antibody::100 µg (0.5 mg/ml) affinity purified rabbit anti-phospho-JNK/SAPK polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Purification method::Affinity purified
This antibody has been succesfully tested for use in following methods::Western blot
Recommended usage::Western blotting (1-2 µg/ml), immunoprecipitation (10-20 µg/ml), immunocytochemistry (10-20 µg/ml), and Immunohistochemistry (20-30 µg/ml). However, the optimal conditions should be determined individually. The antibody detects the p46 and p54 JNK/SAPK dually phosphorylated at Thr183 and Tyr185.
Storage information::Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions::gel pack
How to handle this antibody::The antibody solution should be gently mixed before use.
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties:If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation:anticorps

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