anti-CRTH2 Polyclonal Antibody

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About product

Catalog number:A1064-50
Name:anti-CRTH2 Polyclonal Antibody
Size:CRTH2 Polyclonal Antibody
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Extra details

Target of this antibody::CRTH2
Alternative names of antibody target::CRTH2 Antibody: DP2, DL1R, CD294, CRTH2, GPR44, Prostaglandin D2 receptor 2, Chemoattractant receptorhomologous molecule expressed on Th2 cells
Background information::The chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) is a recently identified receptor for the prostaglandin D2 (PGD2) in addition to the classic prostaglandin D receptor. CRTH2 is expressed on Th2 cells and eosinophils and mediates chemotaxis of these cells to PGD2 and is thus thought to be a key receptor mediating eosinophil and Th2 recruitment during allergic responses. However, CRTH2-null mice showed enhanced eosinophil recruitment into the lung consistent with observations that the CRTH2-null mice produced significantly higher amounts of interleukin-5 (IL-5) and IL-3. This suggests that CRTH2 plays a nonredundant role in restricting eosinophilia and allergic response in vivo.
Antibody host::Rabbit
Clonality of antibody::Polyclonal
Isotype::Rabbit IgG
This antibody reacts with::Human, Mouse, Rat
Immunogene sequence::18 amino acid synthetic peptide from near the amino terminus of human CRTH2.
Concentration of antibody::1 mg/ml
Form of antibody::Liquid
Formulation of this antibody::50 µg (1mg/ml) of antibody in PBS containing 0.02% sodium azide.
This antibody has been succesfully tested for use in following methods::WB, IHC, IF
Recommended usage::WB-1 μg/ml, IHC-P-2.5 μg/ml, IF- 20 μg/ml
Storage information::Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions::gel pack
How to handle this antibody::The antibody solution should be gently mixed before use
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties:If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group:Polyclonals and antibodies
About:Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation:anticorps

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