Bioxys

anti-CTLA4 Polyclonal Antibody

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About product

Catalog number:A1083-100
Name:anti-CTLA4 Polyclonal Antibody
Size:CTLA4 Polyclonal Antibody
Price:219.00
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Extra details

Target of this antibody::CTLA4
Alternative names of antibody target::Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4, CD152
Background information::CTLA4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Antibody host::Rabbit
Clonality of antibody::Polyclonal
Isotype::Rabbit IgG
Clone::N/A
This antibody reacts with::Human
Immunogene sequence::KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human IDDM12.
Form of antibody::Liquid
Formulation of this antibody::PBS with 0.09% (W/V) sodium azide
Purification method::Protein A column, followed by peptide affinity purification.
This antibody has been succesfully tested for use in following methods::WB, IHC-P
Recommended usage::WB: 1:2000IHC-P: 1:50~100
Storage information::Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions::gel pack
How to handle this antibody::The antibody solution should be gently mixed before use
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties:If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Group:Polyclonals and antibodies
About:Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
French translation:anticorps

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