Bioxys

Anti-DNCLI1 (Polyclonal), ALEXA Fluor 350

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About product

Catalog number:GENTObs-20152R-A350
Name:Anti-DNCLI1 (Polyclonal), ALEXA Fluor 350
Size:100 microliters
Price:489.00
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Extra details

Type:Conjugated Primary Antibody
Conjugated with:ALEXA FLUOR® 350
Host organism:Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:DNCLI1
Specificity:This antibody reacts specifically with DNCLI1 ALEXA FLUOR® 350
Modification:No modification has been applied to this antibody
Modification site:None
Clonality:Polyclonal Antibody
Clone:Polyclonal Antibodies
Concentration:1ug per 1ul
Subcellular locations:Cytoplasm
Antigen Source:KLH conjugated synthetic peptide derived from human DNCLI1
Gene ID:51143
Swiss Prot:Q9Y6G9
Applications:IF(IHC-P)
Applications with corresponding dilutions:IF(IHC-P)(1:50-200)
Cross reactive species:Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details:No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information:Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Purification method:Purified by Protein A.
Storage:Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission:343nm/442nm
Synonyms:LIC1; DNCLI1; Cytoplasmic dynein 1 light intermediate chain 1; Dynein light chain A; DLC-A; Dynein light intermediate chain 1, cytosolic; DYNC1LI1
Also known as:DNCLI1 Polyclonal Antibody ALEXA FLUOR® 350
Other name:Anti-DNCLI1 Polyclonal ALEXA FLUOR® 350
Advisory:Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties:For facs or microscopy Alexa 1 conjugate.Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode.
Conjugation:Alexa Fluor,ALEXA FLUOR 350
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group:Polyclonals and antibodies
About:Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

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