Sheep Polyclonal IgG Anti-IgG4, human

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Catalog number:IGG4001
Name:Sheep Polyclonal IgG Anti-IgG4, human
Size:1 ml
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Availability:Please contact us to check the availability
Immunogen:Purified human IgG4
Specificity:human IgG4
Species reactivity:Human
Product presentation:Affinity purified antibody in GBS, pH7.4, 0,099% NaN3, 0,1% EACA, 1 mM EDTA, 0,01% Benzamidine
Product category:Primary Antibody
Antibody's raised in:Sheep
Antibody's isotype:IgG
Antibody's clone:polyclonal
Product is supplied as:liquid concentrate
Recommended concentration for use:1:20
Protein concentration:0,1 mg/ml
Tested applications:IEP, WB, ELISA, Immunohistochemistry
Storage method:Store at 2-8°C
Litterature:1. Kleger A, Seufferlein T, Wagner M, Tannapfel A, Hoffmann TK, Mayerle J (2015) IgG4-associated autoimmune diseases—polymorphous presentation complicates diagnosis and treatment. Dtsch Arztebl Int; 112: 128–35. 2. Stone et al. (2012). Recommendations for the nomenclature of IgG4-related disease and its individual organ system manifestations. Arthritis & Rheumatism. 64 (10): 3061–3067. 3. Deshpande et al. (2012). Consensus statement on the pathology of IgG4-related disease. Modern Pathology. 25 (9): 1181–1192. 4. A. Fernandez-Flores (2012) The role of IgG4 in cutaneous pathology. Rom J Morphol Embryol, 53(2):221-231.
Tips:*Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!
Description:This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties:Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About:Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Additional isotype:IgG
Group:Polyclonals and antibodies

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